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Apheresis Units, Therapeutic, Stem Cell Harvesting

Definition : Apheresis units primarily designed to automate the removal of hematopoietic stem cells (HSC), from the peripheral blood of a patient, close relative, or other appropriate donor. Typically, peripheral blood is collected and mononuclear white blood cells and peripheral blood stem cells are harvested in a blood cell separator and transferred to a collection bag while the other blood components (plasma, red blood cells, platelets) are returned to the patient. These apheresis units usually consist of a disposable pheresis set (i.e., a tubing set that connects the patient to the apheresis unit); pumps (e.g., rotary peristaltic pumps); a centrifugation chamber or membrane filtration unit; centrifugation bowls; dedicated cartridge separators; clamps, controls (e.g., centrifuge and pump speed, volume of solution added); alarms; and bubble detectors. One or two HSC harvests are usually sufficient to obtain enough cells from normal allogeneic donors, but in autologous cases some patients may have to undergo three, four, or more daily apheresis procedures; the collected cells can be used in bone marrow transplantation usually after chemotherapy procedures.

Entry Terms : "Stem Cell Harvesting Apheresis Units, Therapeutic"

UMDC code : 32817

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Biosafe America Inc

Company Type: Parent

Gardner Denver Inc

Company Type: Parent

Gardner Denver, founded in 1859, is a global manufacturer of industrial compressors, blowers, pumps, loading arms and fuel systems. The Company has 40 manufacturing facilities located in the Americas, EMEA and Asia Pacific with offices in 36 different countries. 2010 Revenues were $1.9 billion dollars with approximately 66% of that revenue coming from outside of the United States. The Company believes its major products are leaders within the industries it serves.

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